文劍明,主任醫(yī)師,教授,博士導師,博士,臨床病理診斷。 主要研究方向: 腫瘤病理,腫瘤細胞培養(yǎng)和應用,分子病理。 科研基金: 2004年教育部留學回國人員科研啟動基金:非去極化季松藥對骨骼肌不同肌松效應的形態(tài)學研究(參與) 2005年廣東省自然科學基金:細胞因子協(xié)同EB病毒促進鼻咽癌侵襲轉(zhuǎn)移的差異蛋白質(zhì)組學證據(jù)(參與) 2006年教育部高等學校博士學科點專項科研基金:新抑癌基因ZHX2在肝細胞癌沉默機制沉默機制及對AFP的調(diào)控研究(負責) 社會兼職: 廣州市公安局刑事警察支隊法醫(yī)醫(yī)學顧問 中國抗癌協(xié)會神經(jīng)腫瘤專業(yè)委員會第一屆委員會常委 中華醫(yī)學會病理學分會腦神經(jīng)病理專業(yè)學組委員 中華醫(yī)學會廣東省和廣州市醫(yī)療事故技術鑒定委員會專家 獲獎情況: 2005年 獲教育部科學技術獎一等獎(第六名) 論著: 近5年(2004~2009年)在SCI收錄期刊發(fā)表論文 1. Hu L, Wen JM, Sham JST, Wang WS, Xie D, Tjia WM, Huang JF, Zhang M, Zeng WF, Guan XY. Establishment of cell lines from a primary hepatocellular carcinoma and its metastatis. Caner Genet Cytogenet 2004;148:80-84 2. Hu L, Lau SH, Tzang CH, Wen JM, Wang WS, Xie D, Huang MH, Wang Y, Wu MC, Huang JF, Zeng WF, Sham JST, Yang MS, Guan XY. Association of vimentin overexpression and hepatocellular carcinoma metastasis. Oncogene 2004 Jan 8; 23(1): 298-302 3. Luo B, Sun G, Zhang B, Liang K, Wen J, Fang K. Neuroradiological findings of intracranial schwannomas not arising from the stems of cranial nerves. Brit J Radiol 2004;77:1016-1021 4. Zhang B, Luo B, Zhang Z, Sun G, Wen J. Central neurocytoma: a clinicopathological and neuroradiological study. Neuroradiol 2004;46:888-895 5. Xie D, Zeng WF, Che LH, Zhang M, Wu hx, Lin HL, Wen JM, Lau SH, Hu L, Guan XY. Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression. World J Gastroenterol 2005;11(21):3285-3289 6. Xie D, Zeng YX, Wang HJ, Tai LS, Wen JM, Tao Y, Ma NF, Hu L, Sham JST, Guan XY. Amplification and overexpression of epidermal growth factor receptor gene in glioblastomas of Chinese patients correlates with patient’s age but not with tumor’s clinicopathological pathway. Acta Neuropathol 2005;110:481-489 7. Lv ZL, Luo DZ, Wen JM. Expression and significance of tumor-related genes in HCC. World J Gastroenterol. 2005; 11(25): 3850-3854. 8. Xie D, Zeng YX, Wang HJ, Wen JM, Tao Y, Sham JST, Guan XY. Expression of cytoplasmic and nuclear Survivin in primary and secondary human glioblastoma. Bri J Cancer 2006;......
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