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林靜雯
其他科室
醫(yī)生介紹
1. 職稱(chēng):研究員
2. 學(xué)歷:博士
3. 研究方向: 運(yùn)用系統(tǒng)免疫學(xué)方法研究機(jī)體對(duì)包括瘧疾在內(nèi)傳染病的反應(yīng);利用系統(tǒng)生物學(xué)手段及基因修飾技術(shù)研究篩選新藥、疫苗靶點(diǎn)。
4.郵箱:lin.jingwen@scu.edu.cn
5. 個(gè)人經(jīng)歷
2016年12月-至今,四川大學(xué)華西第二醫(yī)院研究員
2013年3月-2016年10月,UKMedical Research Council Career Development Fellow,The Francis Crick Institute (原National Institute forMedical Research),英國(guó)
2008年10月-2013年2月,博士,LeidenUniversity Medical Center,荷蘭
6. 代表論文:
(1) ? ? ? ? Lin JW*, Sodenkamp J, Cunningham D, et al,Langhorne J* (2017). Signatures of malaria-associated pathology revealed byhigh-resolution whole-blood transcriptomics in a rodent model of malaria. Sci Rep. (co-corresponding authors).
(2) ? ? ? ? Brugat T, Reid AJ, Lin JW, etal (2016). Antibody-independentclonal selection regulates the establishment of chronic Plasmodium infection. NatureMicrobiology.
(3) ? ? ? ? Capuccini B, Lin J,Talavera-López C, et al (2016). Transcriptomic profiling of microglia revealssignatures of cell activation and immune response, during experimental cerebralmalaria. Sci Rep.
(4) ? ? ? ? Lin JW, Spaccapelo R, Schwarzer E, et al(2015). Replication of Plasmodium inreticulocytes can occur without hemozoin formation, resulting in chloroquineresistance.J Exp Med.
(5) ? ? ? ? Salman AM,Mogollon CM, Lin JW, et al (2015).Generation of transgenic rodent malaria parasites expressing human-malariaparasite proteins. Methods Mol Biol.
(6) ? ? ? ? Lin JW, Shaw TN, Bouchier P, et al (2014) Thesubcellular location of ovalbumin in Plasmodiumberghei blood stages influences the magnitude of T-cell responses. Infect Immun.
(7) ? ? ? ? Ezougou CN,Ben-Rached F, Moss DK, Lin JW, et al(2014) Plasmodium falciparum Rab5B isN-terminally myristoylated and targeted to the parasite’s plasma and foodvacuole membranes. PLoS One.
(8) ? ? ? ? Lin JW, Meireles P, PrudêncioM,et al (2013) Loss-of-function analyses definesvital and redundant functions of the plasmodium rhomboid proteasefamily. Molecular Microbiology.
(9) ? ? ? ? Annoura T,van Schaijk BCL, Ploemen IHJ, Sajid M, LinJW, et al (2013) New members
醫(yī)生擅長(zhǎng)
運(yùn)用系統(tǒng)免疫學(xué)方法研究機(jī)體對(duì)包括瘧疾在內(nèi)傳染病的反應(yīng);利用系統(tǒng)生物學(xué)手段及基因修飾技術(shù)研究篩選新藥、疫苗靶點(diǎn)。