醫(yī)生介紹
1.職稱：研究員
2.學歷：博士
3.研究方向：調控心臟發(fā)育的新作用因子及其分子作用機制；生心祖細胞的新亞群及其分子標記的分離；心臟譜系細胞體外定向分化方法的探索與優(yōu)化。
4.郵件：xuez@scu.edu.cn
5.個人經(jīng)歷：
2014.3—2017.7.1博士后，美國麻省理工學院
2014.3—2017.8 ?2009.1—2014.2博士，美國德克薩斯西南醫(yī)學中心—達拉斯分校
6.代表性論文：
(1)Xue, Z., Ye, Q., Anson, S.R., Yang, J., Xiao, G., Kowbel, D., Glass, N.L., Crosthwaite, S.K., and Liu, Y. (2014). Transcriptional interference by antisense RNA is required for circadian clock function. Nature 514, 650-653. (IF=38.1)
(2)Xue, Z., Hennelly, S., Doyle, B., Gulati, A.A., Novikova, I.V., Sanbonmatsu, K.Y., and Boyer, L.A. (2016). A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage. Mol Cell 64, 37-50. (Highlighted by Mol Cell, Nature Chemical Biology, and Science Signaling) (IF=14.0)
(3)Xue, Z., Yuan, H., Guo, J., and Liu, Y. (2012). Reconstitution of an Argonaute-dependent small RNA biogenesis pathway reveals a handover mechanism involving the RNA exosome and the exonuclease QIP. Mol Cell 46, 299-310. (IF=14.0)
(4)Lee, H.C.*, Li, L.*, Gu, W.*, Xue, Z., Crosthwaite, S.K., Pertsemlidis, A., Lewis, Z.A., Freitag, M., Selker, E.U., Mello, C.C., Liu, Y. (2010). Diverse pathways generate microRNA-like RNAs and Dicer-independent small interfering RNAs in fungi. Mol Cell 38, 803-814. (IF=14.0)
(5)Zhang, Z.*, Chang, S.S.*, Zhang, Z., Xue, Z., Zhang, H., Li, S., and Liu, Y. (2013). Homologous recombination as a mechanism to recognize repetitive DNA sequences in an RNAi pathway. Genes Dev 27, 145-150. (IF=10.0)
(6)Yang, Q., Li, L., Xue, Z., Ye, Q., Zhang, L., Li, S., and Liu, Y. (2013). Transcription of the major Neurospora crassa microRNA-like small RNAs relies on RNA polymerase III. PLoS Genet 9, e1003227. (IF=6.7)
(7)Dang, Y., Li, L., Guo, W., Xue, Z., and Liu, Y. (2013). Convergent transcription induces dynamic DNA methylation at disiRNA loci. PLoS Genet 9, e1003761. (IF=6.7)
(8)Dang, Y., Yang, Q., Xue, Z., and Liu, Y. (2011). RNA interference in fungi: pathways, functi
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